MOTS‑C 10mg

MOTS‑C is a mitochondrial‑derived peptide (MDP) consisting of 16 amino acids and encoded within the 12S rRNA region of mitochondrial DNA. As a regulator of cellular energy metabolism, MOTS‑C has become an important research tool in studies involving metabolic function, mitochondrial biology, exercise physiology, and aging. This peptide is ideal for advanced laboratory studies requiring precision, purity, and reproducibility.

• Product Name: MOTS‑C 10mg
• Catalogue Number: MOTSC-010
• Molecular Formula: C190H296N52O58
• CAS Number: 1466113‑63‑8
• Molecular Weight: 2173.3 g/mol
• Purity: ≥99%
• Compound Type: Mitochondrial‑Derived Peptide (MDP)
• Form: Lyophilised Peptide Powder – What is this? Read more here.

Why Is MOTS‑C of Interest to the Research Community?

MOTS‑C is a unique peptide encoded by mitochondrial DNA rather than nuclear DNA, giving it a distinct role in cellular energy regulation. Research shows that MOTS‑C activates the AMPK pathway, a master regulator of metabolic homeostasis, and plays a role in adapting cells to metabolic stress.

Studies have highlighted several areas of scientific interest:

• Energy metabolism regulation — MOTS‑C influences glucose utilisation and fatty acid oxidation
• Improved insulin sensitivity — particularly in skeletal muscle
• Enhanced exercise performance — linked to improved mitochondrial efficiency
• Anti‑inflammatory effects — via MAP kinase pathway modulation
• Potential longevity and anti‑aging effects — due to its role in stress adaptation and mitochondrial signalling

Because MOTS‑C levels naturally decline with age, it is widely studied in the context of metabolic disorders, age‑related decline, and mitochondrial dysfunction.

Usage and Storage:

MOTS‑C is supplied as a lyophilised peptide powder to ensure maximum stability and ease of handling in research environments. For best results, follow our website’s detailed reconstitution and storage guidelines.

Learn more about peptide storage

Synthesis and Quality Assurance:

Our MOTS‑C is synthesised using controlled peptide manufacturing processes designed to ensure high purity, structural accuracy, and batch‑to‑batch consistency. Each batch undergoes stringent purification and analytical testing to meet the rigorous standards required for advanced scientific research.

Why Choose Simply Peptides for MOTS‑C in the UK?

Simply Peptides is committed to providing research‑grade compounds of uncompromising quality. Through direct manufacturing partnerships, we maintain full oversight of production standards and batch consistency. Researchers across the UK and internationally trust our transparent testing, rigorous quality control, and dependable supply chain.

Is This Product for Human Use?

No. This material is for research only and is not intended for human consumption or clinical applications.

External Resources for Researchers

• PubMed — MOTS‑C (search)
• Google Scholar — MOTS‑C literature

Alternative Names for MOTS‑C

• Mitochondrial ORF of the 12S rRNA type‑C
• Mitochondrial‑Derived Peptide (MDP)
• MRWQEMGYIFYPRKLR – Amino acid sequence

Legal and Safety Information:

Simply Peptides supplies MOTS‑C strictly for scientific and research use. Our products are not intended for human consumption or clinical application. We uphold stringent quality and legal compliance standards to support the research community.

COA & Testing Reports

Certificate of Analysis (COA) & Independent Testing

Each batch of MOTS‑C is accompanied by a Certificate of Analysis (COA), verifying identity, purity, and composition using validated analytical methods. This ensures transparency and supports research integrity.

In addition to internal quality control, we commission independent third‑party analysis to confirm peptide purity, molecular weight, and absence of contaminants. These reports are available upon request to qualified research professionals.

• Batch‑specific COA are available for download or review here
• Third‑party lab testing for purity and identity confirmation are available here
• Analytical methods include HPLC, Mass Spectrometry, and Microbial Screening here

Note: All documentation is provided for research reference only and is not intended to support clinical or therapeutic claims.